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Catalog Number: CST26912
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Gene Symbol: RAP1
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Description: Anti Active Rap1 Mouse Monoclonal Antibody
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Background: Small GTPases are a super-family of cellular signaling regulators. Rap family members (Rap1A, Rap1B, Rap2A, Rap2B, and Rap2C) are Ras-like GTPases that regulate cell proliferation, differentiation, apoptosis and adhesion mechanisms. Rap1 (Ras-proximate-1) regulates apoptosis through interaction with two MAP3K effectors of the MEK/ERK MAP-kinase pathway, Raf-1 and B-Raf. Rap1 regulates cell adhesion mechanisms through effector molecules such as the integrins and cadherins.
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Immunogen: Recombinant full length protein of active Rap1.
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Applications: IP, IHC
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Recommended Dilutions: 1 μg for 1~2 mg total cellular proteins for IP
1:100 dilution for IHC
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Concentration: 1 mg/ml
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Host: mouse
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Format: Liquid
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Clonality: Monoclonal
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Isotype: IgG
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Purity: Purified from ascites
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Storage buffer:
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Preservative: no
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Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Species Reactivity: Anti-active Rap1 antibody recognizes active Rap1 of vertebrates.
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Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles
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Immunoprecipitation/Western blot:
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