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Catalog Number: CST26146
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Gene Symbol: RET, PTC, CDHF12, CAHF16, HSCR1, MEN2A, MEN2B
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Description: Anti RET(C634Y) Mouse Monoclonal Antibody
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Background: RET protein is encoded by the RET proto- oncogene. It is a receptor tyrosine kinase. RET loss of function mutations are associated with the development of Hirschsprung’s disease, while gain of function mutations are associated with development of various types of human cancer, including medullary thyroid carcinoma, multiple endocrine neoplasias type 2A and 2B, pheochromocytoma and parathyroid hyperplasia.
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Immunogen: A synthetic peptide from the internal region of RET which includes the mutation of C634Y, human origin.
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Applications: ELISA, WB, IHC
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Recommended Dilutions:
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IHC: 1:50-1:100
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Concentration: 0.5 mg/ml
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Host: Mouse
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Format: Liquid
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Clonality: Monoclonal
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Isotype:
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Purity: Purified from ascites
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Storage buffer:
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Preservative: no
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Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Species Reactivity: Recognizes C634Y mutant, but not wild-type RET of vertebrates.
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Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles
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Western blot:
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