Catalog No. 

CS543046

Species reactivity 

Human

Applications 

Research Grade Biosimilar

Host species 

Humanized

Isotype 

IgG1-Lambda

Expression system

Mammalian Cells

Clonality

Monoclonal

Target 

NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11

Concentration 

1mg/ml

Endotoxin level

Please contact the lab for this information.

Purity 

>95% purity as determined by SDS-PAGE.

Purification 

Protein A/G, purified from cell culture supernatant.

Accession

O95760

Form 

Liquid

Storage buffer

0.01M PBS,pH7.4.

Stability and Storage 

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -682°C.

Alternate Names 

MEDI-3506,CAS:2376858-66-9

Background 

Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. Tozorakimab reduces inflammation and epithelial dysfunction. Tozorakimab can be used to research chronic obstructive pulmonary disease.

Note 

For research use only. Not for use in clinical or therapeutic applications.