Catalog No. 

CS546066

Species reactivity 

Human

Applications 

Research Grade Biosimilar

Host species 

Chimeric

Isotype

IgG1-Kappa

Expression system 

Mammalian Cells

Clonality 

Monoclonal

Target

Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen

Concentration 

1mg/ml

Endotoxin level

Please contact the lab for this information.

Purity

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G, purified from cell culture supernatant.

Accession 

P06731

Form 

Liquid

Storage buffer

0.01M PBS,pH7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -711°C.

Alternate Names

SAR-408377,CAS:2349294-95-5

Background 

Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative).

Note

For research use only. Not for use in clinical or therapeutic applications.