Catalog No.

CS145016

Species reactivity

Human

Applications 

Research Grade Biosimilar

Host species

Human

Isotype 

IgG4-kappa

Expression system

Mammalian Cells

Clonality 

Monoclonal

Target 

Herpes virus entry mediator ligand, LIGHT, CD258, HVEM-L, HVEML, TNFSF14, Tumor necrosis factor ligand superfamily member 14, Herpesvirus entry mediator ligand

Concentration 

1mg/ml

Endotoxin level 

Please contact the lab for this information.

Purity 

>95% purity as determined by SDS-PAGE.

Purification 

Protein A/G, purified from cell culture supernatant.

Accession 

O43557

Form 

Liquid

Storage buffer 

0.01M PBS,pH7.4.

Stability and Storage 

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -759°C.

Alternate Names 

AEVI-002,CERC-002,F-19,MDGN-002,SAR-252067CAS:2427667-03-4

Background 

Quisovalimab (AVTX-002; AEVI 002; SAR 252067) is a human monoclonal antibody against LIGHT, a tumor necrosis factor (TNF)-related cytokine (TNFSF14) that plays an important role in acute respiratory distress syndrome (ARDS) and cytokine release syndrome (CRS) COVID-19. Quisovalimab can be used in COVID-19 acute respiratory distress syndrome and other studies.

Note

For research use only. Not for use in clinical or therapeutic applications.