Catalog No.

CS885016

Species reactivity 

Human

Applications

Research Grade Biosimilar

Host species

Humanized

Isotype

IgG2-kappa

Expression system 

Mammalian Cells

Clonality

Monoclonal

Target

Leukocyte-endothelial cell adhesion molecule 3, Platelet activation dependent granule-external membrane protein, Granule membrane protein 140, GMP-140, CD62P, SELP, GRMP, PADGEM, CD62 antigen-like family member P, LECAM3, P-selectin, GMRP

Concentration 

6.06mg/ml

Endotoxin level 

Please contact the lab for this information.

Purity 

>95% purity as determined by SDS-PAGE.

Purification 

Protein A/G, purified from cell culture supernatant.

Accession

P16109

Form 

Liquid

Storage buffer 

0.01M PBS,pH7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -621°C.

Alternate Names 

SelG1,CAS:1690318-25-2

Background 

Crizanlizumab is an anti-P-selectin monoclonal antibody. Crizanlizumab binds to P-selectin and blocks its interaction with P-selectin glycoprotein ligand 1 (PSGL-1). Crizanlizumab prevents vaso-occlusive crises (VOCs) and can be used for research of sickle cell disease.

Note 

For research use only. Not for use in clinical or therapeutic applications.