Catalog No. 

CS338036

Species reactivity 

Human

Applications

Research Grade Biosimilar

Host species

Humanized

Isotype 

IgG4

Expression system 

Mammalian Cells

Clonality 

Monoclonal

Target 

FLK-1, Kinase insert domain receptor, VEGFR2, Fetal liver kinase 1, CD309, Vascular endothelial growth factor receptor 2, Protein-tyrosine kinase receptor flk-1, FLK1, VEGFR-2, KDR

Concentration 

1mg/ml

Endotoxin level

Please contact the lab for this information.

Purity 

>95% purity as determined by SDS-PAGE.

Purification 

Protein A/G, purified from cell culture supernatant.

Accession 

P35968

Form

Liquid

Storage buffer

0.01M PBS,pH7.4.

Stability and Storage 

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -255°C.

Background

Alacizumab is a CHO-expressed humanized antibody that targets VEGFR2/KDR/Flk-1/VEGFR2/KDR/Flk-1/CD309. Alacizumab contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 144.08 kDa. The isotype control for Alacizumab can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

Note 

For research use only. Not for use in clinical or therapeutic applications.