Catalog No. 

CS063016

Description 

SAR566658(SAR)isamaytansinoid-loadedADC(huDS6-SPDB-DM4)targetingCA6,aspecificglycol-epitopeofMUC-1over-expressedinsolidtumors(pancreas26%,ovary55%,breast30%,bladder60%)andrarelyinnormaltissues.AntibodysystemcanprovideuncoupledantibodyagainstCA6,aspecificglycol-epitopeofMUC-1.

Species reactivity

Human

Applications 

Research Grade Biosimilar

Host species 

Human

Isotype

IgG

Expression system

Mammalian Cells

Clonality 

Monoclonal

Target

PEMT, CA 15-3, H23AG, Peanut-reactive urinary mucin, PEM, EMA, Cancer antigen 15-3, MUC-1, Episialin, MUC1-CT, MUC1-beta, Tumor-associated mucin, CD227, Polymorphic epithelial mucin, KL-6, MUC1-alpha, MUC1, PUM, Krebs von den Lungen-6, MUC1-NT, Tumor-associated epithelial membrane antigen, Mucin-1, Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin

Concentration

1mg/ml

Endotoxin level 

Please contact the lab for this information.

Purity

>95% purity as determined by SDS-PAGE.

Purification 

Protein A/G, purified from cell culture supernatant.

Accession 

P15941

Form

Liquid

Storage buffer 

0.01M PBS,pH7.4.

Stability and Storage 

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -978°C.

Alternate Names 

SAR-566658,SAR566658,SAR566658

Note 

For research use only. Not for use in clinical or therapeutic applications.