抗体类型 Primary Antibodies
免疫原 Polypeptide
克隆性 Polyclonal
同种型 IgG
宿主 Rabbit
来源 Rabbit
已测试的应用 ELISAICC/IFIF-PIHCWB
物种反应性 HumanMouseRat
浓度 1mg/ml
纯化 Protein A
基因名称 AKR1C1/AKR1C2
基因别名 AKR1C1; AKR1C2
基因全称 aldo-keto reductase family 1 member C1/aldo-keto reductase family 1 member C2
基因简介 This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]/This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
蛋白别名 20 alpha (3 alpha) hydroxysteroid dehydrogenase antibody;20-alpha-HSD antibody;20-alpha-hydroxysteroid dehydrogenase antibody;3-alpha-HSD3 antibody;AKR1C1 antibody;AKR1C2 antibody;Aldo-keto reductase family 1 member C1 antibody;Aldo-keto reductase family 1 member C2 antibody;Chlordecone reductase homolog HAKRC antibody;Chlordecone reductase homolog HAKRD antibody
分子量 37kDa
Uniprot ID Q04828/P52895
应用稀释比 IHC:1:200-1:2000
ICC/IF:1:100-1:500
WB:1:1000-1:2000
IF-P:1:200-1:2000
ELISA:1:1000-1:10000
修饰 Unmodification
标记 Unconjugated
亚细胞定位 Cytoplasm, cytosol
产品形态 Liquid
缓冲液 Purified antibody in PBS with 0.05% PC300,40% Glycerol.

保存条件 Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

For research use only .